CONSENSUS
STATEMENT
FIRST
INTERNATIONAL CONFERENCE FOR THE
PREVENTION
OF INCONTINENCE
DANESFIELD HOUSE U.K. JUNE 25-27 1997
INTRODUCTION
A: CLINICAL DEFINITION
B: THE CONCEPT OF PREVENTION
C: HEALTHY BLADDER HABITS
D: INCONTINENCE PREVENTION BY AGE GROUP
- PREVENTION IN CHILDHOOD
- PREVENTION IN YOUNG ADULTS
- PREVENTION IN THE MIDDLE YEARS
- PREVENTION IN HEALTHY OLDER
ADULTS
- PREVENTION IN FRAIL OLDER
ADULTS
E: PROMOTING PREVENTION EDUCATION BY TARGET GROUP
IntroductionA
two day conference was convened at the Danesfield House U.K. with
the intent of creating a Consensus Statement which would guide and
direct future clinical practice and research for the Prevention of
Incontinence.
First conceived during discussions of the Continence Promotion Committee
at the 1996 ICS (International Continence Society) meeting in Athens
it was through the outstanding initiative of The Simon Foundation
for Continence (USA) and The Continence Foundation (UK) that the First
International Conference for the Prevention of Incontinence (P97)
was realised.
Forty two internationally recognised experts in the field came together
to examine and critique current research. Rigorous intellectual debate
followed each of the dozen presentations.
The dynamic interaction and collaboration of panel, presenters and
expert audience was as stimulating as it was productive. Pieces of
the prevention puzzle emerged as presentations and debates progressed.
This Consensus Statement is the outcome of these two days in June.
Special mention is due Dr. Alan Cottenden, panel chair, and conference
co-chairs Cheryle Gartley, Christine Norton and Anita Saltmarche for
their substantial contributions to this endeavour.
Without an educational grant from Pharmacia & Upjohn, and the personal
sacrifice and professional commitment of all participants the P97
conference would have remained an idea in Athens.
This Consensus Statement was first issued at the 1997 International
Continence Society meeting in Yokohama, Japan.
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A
CLINICAL DEFINITION
URINARY INCONTINENCE
Since there are numerous definitions of Urinary Incontinence,
it was agreed that the International Continence Society definition
be adopted by the Conference.
Urinary Incontinence 'is a condition in which involuntary urine
loss is a social or hygienic problem and is objectively demonstrable'.
However, the 'objectively demonstrable' criteria may require modification
in large-scale epidemiological work.
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B
THE CONCEPTION OF PREVENTION
While there are different models of prevention,
the following definitions related to prevention were used as points
for discussion. It was noted that these definitions are embedded in
a disease model.
PRIMARY PREVENTION
Preventing disease from occurring by removing its causes.
SECONDARY PREVENTION
Detecting asymptomatic disease early and treating it to stop progression.
TERTIARY PREVENTION
Activities that prevent deterioration or reduce complications
after a disease has declared itself.
THE IMPAIRMENT-DISABILITY-HANDICAP MODEL
Recognising that incontinence is not a disease but is a symptom or
condition the panel felt it may be necessary to consider a prevention
model similar to the Rehabilitation model of Impairment~Disability-Handicap.
Using this model, impairment would be the underlying bladder or sphincter
dysfunction (or dysfunction of the neurological control system at
any level). Disability would be the consequent symptom of incontinence.
The limitations imposed on the individual's quality of life are the
handicap. Therefore, primary prevention would be aimed at preventing
the underlying impairment from developing. Secondary prevention
would be preventing the individual, despite an underlying predisposition,
from becoming incontinent. Tertiary prevention would be preventing
incontinence from worsening, or causing complications (such as skin
problems) or limiting the impact of being incontinent upon the individual
and those around them.
QUALITY OF LIFE
Quality of life was a recurring theme at the conference. Although
the concept is frequently addressed in research, it is often not clearly
defined. It was agreed that the outcome of any prevention strategy
should be assessed not only in terms of bladder function, but also
should incorporate the individual's perspective. Quality of life outcomes
need to include overall benefits to both the individual and society
as a whole. It was recognised that prevention programmes are likely
to be costly. Consequently, future prevention research should consider
a cost-benefit analysis.
It was agreed that the focus of this meeting should be on primary
and secondary prevention as treatment and containment are discussed
and researched elsewhere. It was further agreed that some primary
prevention measures, such as those aimed at preventing neurological
disease or injury (with subsequent incontinence) were beyond the scope
of this conference.
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C HEALTHY
BLADDER HABITS
P97 participants agreed that the promotion of prevention
is essential and therefore developed these recommendations.
Drink Adequately:
6-8 cups of fluids per day, more when it is hot or when exercising.
Recognise
that:
Most
people empty the bladder about every 3-4 hours during the day
( 4-8 times in 24 hours). Getting up once at night to empty the
bladder is not abnormal. Being awakened more than twice is abnormal.
Relax:
Don't
strain to empty the bladder or the bowel.
Try
to keep bowel movements regular:
Don't
ignore feelings that the bowels need emptying.
Seek
professional help when:
Any leakage of urine from the bladder occurs (incontinence). Pain
is experienced when passing urine. Any blood is seen in urine.
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TO TOP OF PAGE
D INCONTINENCE
PREVENTION
BY
AGE GROUP
PREVENTION IN CHILDHOOD
Clinical
Evidence
Indicates what is known about preventing incontinence.
Acquisition
of general continence abilities are probably innate in neurologically
intact humans.
Toileting skills and behaviour that are learned, have a certain
plasticity, and vary across cultures.
Although there are undoubtedly many cultural influences on the
acquisition of toilet skills, we do not have much evidence of
the effect of these on later bladder habits and continence.
There is little evidence that adults with bladder problems pass
on abnormal patterns to their offspring. We do not know if these
have an impact on the genesis of later dysfunction.
Genetic research has identified a marker for one type of nocturnal
enuresis, but not as yet for other bladder dysfunctions.
It is shown that children with severe mental retardation can often
acquire continence if systematically trained using behaviour techniques.
Urinary tract infection in childhood should be investigated and
appropriately treated as there may be long-term adverse sequelae.
Schools and teachers need to promote positive attitudes to toileting
and to promote an open positive culture about bodily functions.
The value of preventive pelvic floor education or bladder awareness
in schools is unproven.
Children with congenital or acquired neurological impairments
are not inevitably incontinent if a systematic planned approach
is implemented early.
Research
priorities
Not in order of priority.
Environmental influence on the acquisition of toileting skills
Longitudinal studies to determine the effect of early training
or childhood dysfunction on continence in later life
Inter-relationship of skills for bladder and bowel continence
PREVENTION
IN YOUNG ADULTS Clinical
Evidence
Indicates what is known about preventing incontinence.
Constipation,
obesity, smoking and some medications (e.g. alpha blockers, caffeine
and diuretics) may be risk factors.
Asymptomatic bacteriuria is not linked to incontinence.
Adults with neurological disease often have inevitable bladder
or sphincter impairment, but active management may prevent this
manifesting as incontinence.
For women, the major risk factor is undoubtedly vaginal delivery
during childbirth.
Caesarean section appears to prevent incontinence, certainly for
the first baby, possibly less so for multiple births.
Vacuum extraction rather than forceps is preferred for assisted
delivery to prevent incontinence.
The relation of episiotomy to incontinence is unclear.
There is weak evidence that antenatal pelvic floor exercise may
be protective in the postnatal period. Longer term benefit is
unproven.
Excessive physical stress during exercise or repeated lifting
may be a risk factor in the development of incontinence in women.
Young men are a low risk group for incontinence (with the exception
of nocturnal enuresis).
Research
priorities
Not in order of priority.
Prospective
studies of risk factors in continent women (including further
work on caffeine, medications and obesity).
Further study the effect of childbirth practices such as episiotomy
and assisted delivery on long-term continence.
Further study on the effect of pre- or post-natal pelvic floor
education and exercise.
Study the effect of exercise and lifting on the pelvic floor.
Prospective study of the effect of constipation in continent females.
Methods to improve bladder emptying and prevent complications
in patients with neurological disease (e.g. does the Crede manoeuvre
create long-term problems?)
PREVENTION
IN THE MIDDLE YEARS
Clinical Evidence
Indicates what is known about preventing incontinence.
Radiotherapy
for pelvic malignancies is associated with increased urinary incontinence.
For women the link with vaginal delivery becomes less clear than
in younger women.
The role of oestrogen and menopause is likewise unclear. It is
not known if hormone replacement therapy (HRT) helps to prevent
the development of urinary incontinence.
Urinary incontinence is clearly linked to obesity in women.
The role of smoking is less clear, as is the role of hysterectomy
and of straining due to chronic constipation.
Sometimes repair of a vaginal prolapse can unmask a tendency to
urinary incontinence.
Incidence of incontinence in women tends to level off with advancing
years; stress incontinence may even decrease with age. Only when
dementia, immobility or general frailty develop does the prevalence
increase with age.
Men continue to be a low risk group, until the age where the prostate
becomes troublesome for some and may need intervention.
Radical prostatectomy is associated with urinary incontinence.
Specialised centres should be developed for the treatment of prostate
cancer (performing more than 20 operations per year), and men
need improved information about incontinence risks to enable an
informed choice on intervention.
Pre-operative detrusor dysfunction may make urinary incontinence
more likely after transurethral resection of the prostate (TURP).
Post-micturition dribbling can often be prevented by simple education.
In men with symptoms suggestive of prostatic hyperplasia and coexisting
Parkinsonism, particular care should be taken not to misdiagnose
Multiple System Atrophy (MSA) as Parkinson's disease. Removal
of the prostate is inadvisable in men with MSA.
Research
priorities
Not in order of priority.
Prospective
study of the effect of hysterectomy on bladder function.
Long-term effects of childbirth, including obstetric practices
and age of childbearing.
Study further the role of collagen.
Investigate the effect of menopause and hormone replacement therapy
on the urinary tract.
Study the effects of prolapse and its repair, other pelvic surgery,
and continence.
Long-term sequelae of untreated obstruction or its medical management
in men.
Prospective study of pre-operative risk factors and continence
after prostatectomy.
Development of a standardized outcome questionnaire, including
continence status, to be used with patients undergoing radical
prostatectomy. Comparison of continence results from different
surgeons and centres.
PREVENTION
IN HEALTHY OLDER ADULTS
Clinical Evidence
Indicates what is known about preventing incontinence.
Investigated Risk Factors
Previous
genito-urinary surgery.
Impaired mobility.
Chronic cough.
Functional disability.
Stroke.
Respiratory illness.
Sedatives and hypnotics.
Faecal incontinence or impaction.
Current
research has not proven the importance of:
bacteriuria
without dysuria, caffeine, alcohol, race, ethnicity.
It was noted that studies have largely been cross-sectional and
have not fully considered the effect of confounding factors.
Research
priorities
Not in order of priority.
Prospective
longitudinal study of these risk factors.
Relationship of urinary and defaecation problems.
Effect of general fitness and mobility.
PREVENTION
IN FRAIL OLDER ADULTS
Clinical Evidence
Indicates what is known about preventing incontinence.
The prevention model outlined in section B. is not appropriate
for many frail older adults who are dependent on caregivers for
toileting and maintaining continence. Therefore the concept of
"Dependent Continence" is most applicable.
Investigated
associations include:
Immobility
Impaired cognition, especially spatial
Drugs, particularly sedatives and diuretics
Complexity of physical environment and barriers (e.g. the number
of points where the individual must make a decision on the way
to the toilet)
Impaired activities of daily living, particularly dressing dependence
Caregiver attitudes/beliefs/knowledge
Disease e.g. Parkinson's, CVA, diabetes, fractured neck of femur
Retention of urine or an elevated post-micturition residual: urologic
causes or post-operative.
Research
priorities
Not in order of priority. Does
identification of co-morbidity lead to improvement?
What are clinically (as opposed to statistically)
relevant outcomes for this group?
Measurement and modification of caregiver attitudes/knowledge/ expectations
and how to change them, with what clinical effect?
Why some individuals with increased risk become incontinent while
others maintain continence.
Catheter management.
Retention and its relevance.
Minimising impact on quality of life for intractable incontinence.
E
PROMOTING PREVENTION EDUCATION
BY
TARGET GROUP
GENERAL PUBLIC
The
panel agreed that extensive education across the following target
groups was necessary to promote prevention of incontinence.
The
general public should be informed about healthy bladder habits
and when/how to seek help.
Parents should know about the possible effects of toilet training
practices and attitudes.
Teachers and schools should be informed about the importance of
healthy bladder habits and appropriate toilet environments.
People with neurological disease (and their doctors) should know
that management is possible.
Relatives of people with existing incontinence might prove the
most receptive and relevant audience to target with a prevention
message. More research is needed to determine the most effective
delivery of continence health education.
HEALTH
PROFESSIONALS / RESEARCHERS
Health professionals would be well advised to incorporate
this knowledge into their everyday clinical practice.
Patients and the general public could benefit from the dissemination
of this knowledge.
We have identified many deficiencies in existing research data. There
is a need to increase the quality of prevention research, to standardize
terminology, and utilize prospective cohort designs for research.
These improvements are necessary despite being both costly and time-consuming.
Standardization of data acquisition, diagnostic methods, interviews,
interventions and measurement are essential. This standardisation
would be best coordinated through the International Continence Society.
It is important that researchers fully understand the implications
of different study designs, and what can and cannot be determined
about causative links.
OTHER GROUPS
Government bodies, especially Health Departments, but
also others including Departments of Education, Employment etc.
Health insurance companies or other health funders as
appropriate in each country.
National organizations and societies whose members or
target audience may have continence risks (such as organizations of
people with neurological diseases), or whose members may have health
care responsibilities for potentially incontinent people (doctors,
nurses and other health professionals). Each group will need a message
specifically targeted to their own areas of interest, to ensure they
take an active role in prevention.
International organizations such as the International
Continence Society (ICS), World Health Organization (WHO), International
Consultation on Incontinence (Monaco 1998), and other health related
organizations all need to work together to ensure a strong and consistent
message is disseminated.
Industry. Companies which produce products to treat
or manage incontinence should be encouraged to use their considerable
communication channels to promote the prevention of incontinence.
THE FUTURE
PROMOTING CONTINENCE
The challenge for professionals will be the integration of this clinical
evidence into practice and promoting and implementing these prevention
strategies. More research is needed to supplement these initiatives.
This Consensus Statement has been published on behalf of all who would
benefit from the implementation of PREVENTION strategies.
CONFERENCE PARTICIPANTS
(cc) Conference Co-Chairs
(pc) Panel Chair
(pm) Panel Members
(s) Speakers
(pl) Planning Committee
Ted Arnold MD
Associate Professor
Department of Urology
Christchurch Hospital
Christchurch
New Zealand
Kari Bo PhD, PT
Associate Professor
Norwegian University of Sports & Physical Education
Oslo, Norway
Linda Brubaker MD (s)
Associate Professor
Department of Obstetrics & Gynecology
Rush Medical College;
Director - Urogynecology & Reconstructive Pelvic Surgery
Rush Presbyterian St. Luke's Medical Center
Chicago, Illinois, U.S.A.
Richard Bump MD (s)
Associate Professor and Chief
Division of Gynecologic Specialties
Duke University Medical Center
Durham, North Carolina, U.S.A.
Kathryn Burgio PhD (s)
Director - Continence Program
Division of Gerontology & Geriatric Medicine and Center for Aging
University of Alabama at Birmingham
Birmingham,Alabama, U.S.A.
Alan Cottenden PhD (pc)
Lecturer in Medical Physics
University College London
London, England
Ananias Diokno MD (s, pl)
Chief - Department of Urology
William Beaumont Hospital
Royal Oak Michigan, U.S.A.
Peter Dwyer MD
Associate Professor
Department of Obstetrics & Gynaecology
Fitzroy, Australia
David Fonda MD (s)
Associate Professor
Director, Aged Care Service Head,
Caulfield Continence Service
Caulfield General Medical Centre
Caulfield, Australia
Clare Fowler MD (s)
Consultant in UroNeurology
National Hospital for Neurology and Neurosurgery
London, England
Cheryle B. Gartley (cc, pl, pm)
President & Founder
The Simon Foundation for Continence
Wilmette, Illinois, U.S.A.
Derek Griffiths PhD (pm)
Urodynamics & Northern Alberta Continence Services
Misericordia Community Hospital & Health Centre
Edmonton, Alberta, Canada
Francine Grodstein ScD (s, pm)
Instructor of Medicine, Channing Laboratory
Department of Medicine
Brigham and Women's Hospital
Harvard Medical School
Boston, Massachusetts, U.S.A.
Sender Herschorn
MD Head, Division of Urology
Sunnybrook Health Science Centre;
Associate Professor
University of Toronto
Toronto, Ontario, Canada
Rudi Janknegt MD
Professor, Department of Urology
University of Maastricht
Maastricht, Netherlands
Steven Kaplan MD (s)
Professor and Vice-chairman
Department of Urology
College of Physicians and Surgeons
Columbia University
New York, New York, U.S.A.
Ruth Kirschner-Hermanns MD (s)
Research Fellow
Gerontology Division
Brigham and Women's Hospital
Harvard Medical School
Boston, Massachusetts, U.S.A.
Jo Laycock PhD, PT
The Culgaith Clinic
Culgaith, England
Gunnar Lose MD
Chief, Department of Obstetrics & Gynaecology
Glostrup, Denmark
Peter Lim MD
President
Society of Continence (Singapore);
Division of Urology
Toa Payoh Hospital
Toa Payoh, Singapore
Helmut Madersbacher MD
Associate Professor of Urology
Head of the Neuro-urology Unit
University Hospital
Innsbruck, Austria
Reverend Colin McLean (pm)
Chairman
Incontact
London, England
Richard Millard MD
Associate Professor
University of New South Wales;
Department of Urology
The Prince Henry Hospital
Sydney, Australia
Katherine Moore PhD
Assistant Professor
Faculty of Nursing
University of Alberta
Edmonton, Alberta, Canada
Kaoru Nishimura
President
Japan Continence Action Society
Tokyo, Japan
Christine Norton MA, RN (cc, pl, pm)
Nurse Specialist - Continence
Northwick Park & St. Mark's Hospital
Middlesex, England
Peggy Norton MD (s, pl)
Associate Professor
Head - Uro-gynecology & Pelvic Reconstructive Surgery
Salt Lake City, Utah, U.S.A.
Leroy Nyberg Jr. MD (pm)
Director Urology Programs
NIH/NIDDK/KUH
Bethesda, Maryland, U.S.A.
David Pollock BA
Director
The Continence Foundation
London, England
Neil Resnick MD (pl)
Chief of Gerontology
Brigham and Women's Hospital;
Associate Professor Harvard Medical School Boston,
Massachusetts, U.S.A.
Brenda Roe PhD, RN (pm)
Professor Institute of Human Aging
University of Liverpool
Liverpool, England
Ron Rozensky PhD (pl, pm)
Professor, Psychiatry & Behavioural Sciences
Northwestern University Medical School;
Associate Chairperson
Department of Psychiatry
Evanston Hospital
Evanston, Illinois, U.S.A.
Anita Saltmarche MHSc, RN (cc, s, pl)
President - Canadian Continence Foundation;
Clinical Associate - Faculty of Nursing
University of Toronto;
President - HealthCare Associates
Toronto, Ontario, Canada
Nigel Smith MD
Senior Clinical Research Fellow
Honorary Consultant
Faculty of Medicine
University of Leicester
Paul Smith PhD (s)
Clinical Psychologist
North Tyneside Health Care NHS Trust
North Tyneside, England
Stuart Stanton MD
Consultant - Urogynaecology
St. George's Hospital Urogynaecology Unit;
Chairman - The Continence Foundation
London, England
Eboo Versi MD
Department of Gynecology & Obstetrics
Brigham & Women's Hospital
Harvard Medical School
Boston, Massachusetts, U.S.A.
Thelma J. Wells PhD, RN (pm)
Helen Denne Schulte Nursing Professor
University of Wisconsin
Madison, Wisconson, U.S.A.
Don Wilson MD
Associate Professor
Department of Obstetrics & Gynaecology
University of Otago
Dunedin, New Zealand
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